Overview and Concepts

نویسندگان

  • C. David Allis
  • Thomas Jenuwein
  • Danny Reinberg
چکیده

1. Genetics Versus Epigenetics, 25 2. Model Systems for the Study of Epigenetics, 26 3. Defining Epigenetics, 28 4. The Chromatin Template, 29 5. Higher-Order Chromatin Organization, 31 6. The Distinction between Euchromatin and Heterochromatin, 34 7. Histone Modifications and the Histone Code, 36 8. Chromatin-remodeling Complexes and Histone Variants, 39 9. DNA Methylation, 41 10. RNAi and RNA-directed Gene Silencing, 42 11. From Unicellular to Multicellular Systems, 44 12. Polycomb and Trithorax, 45 13. X Inactivation and Facultative Heterochromatin, 47 14. Reprogramming of Cell Fates, 49 15. Cancer, 50 16. What Does Epigenetic Control Actually Do? , 52 17. Big Questions in Epigenetic Research, 55 References, 56 C O N T E N T S 03_EPIGEN_p023-062.qxd 9/12/06 11:57 AM Page 23

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تاریخ انتشار 2007